Healthcare organizations are increasingly shifting to home infusion therapy for patients with bleeding disorders.
Patients prefer the in-home infusion approach due to its increased convenience, independence and potential cost savings compared to traditional hospital treatments.
Healthcare organizations prefer this approach because it reduces hospitalizations, increases efficiencies, improves health outcomes and mitigates risks like hospital-acquired infections (HAIs), all of which lead to significant cost savings.
The BrightStar Care® RN-led teams provide specialized expertise in factor replacement therapy and Hemlibra, ensuring safe, effective treatment while helping healthcare organizations reduce clinical risk, maintain consistent quality metrics and strengthen audit readiness.
Understanding Bleeding Disorders and Infusion Therapy
Common Bleeding Disorders Requiring Infusion
The registered nurses at BrightStar Care are skilled and experienced with several bleeding disorders that require infusion, including:
- Hemophilia A and B: Bleeding disorders caused by inherited or spontaneous gene mutations that reduce specific clotting factors. This can lead to easy bruising, bleeding into joints and prolonged bleeding after injuries.
- Von Willebrand disease (vWD): An inherited and lifelong bleeding disorder caused by a deficiency or malfunction of the Von Willebrand factor, a protein that helps blood clot. Severity varies by type:
- Type 1 is usually mild and treated as needed.
- Type 2 can cause noticeable bleeding (e.g., frequent nosebleeds, easy bruising or heavy menstruation).
- Type 3 is rare and the most severe, often requiring more intensive and prophylactic treatment. Symptoms can include prolonged or heavy bleeding.
- Immune thrombocytopenia (ITP): An autoimmune disorder leading to a low platelet count, easy bruising and prolonged or heavy bleeding. Severe cases may be treated with biologics or IVIG (intravenous immunoglobin) to help prevent bleeding.
Fast Facts About Bleeding Disorders
- Hemophilia A affects about one in 5,000 male births in the U.S. and many require ongoing infusion care at home.
- Home-based infusion therapy reduces ER visits, unplanned visits and avoidable admissions, leading to partner cost savings.
- Subcutaneous Hemlibra can be safely administered at home with proper monitoring.
- Home infusion therapy enhances patient independence and quality of life, elevating patient satisfaction ratings.
The Role of Infusion Therapy
Modern treatments, like home infusion therapy, play a life-saving role by delivering clotting factor replacement therapy, providing emergency infusions after trauma and enabling preventive (prophylactic) infusions to reduce the frequency of bleeding events.
- Factor replacement therapy fundamentals
- Prophylactic vs. on-demand treatment
- Evolution toward longer acting and subcutaneous therapies
- Patient quality of life improvements with home infusion
Home infusion nursing for bleeding disorders supports improved treatment adherence, reduced ER visits and better quality of life.
Studies show that intermediate doses of preventative infusion therapy are associated with fewer bleeding events and better overall joint function compared to on-demand treatments in a hospital-based environment.
Key Infusion Therapies for Bleeding Disorders
Home infusion therapy helps patients live fuller, safer lives while supporting healthcare organizations in delivering high-quality and reliable care. BrightStar Care partners with organizations to provide infusion services that prioritize safety, compliance and patient well-being.
Traditional Factor Replacement Products
Factor replacement therapy remains the gold standard in hemophilia home infusion treatment. Recombinant products, proteins made in the lab and plasma-derived products, sourced from donor blood help prevent bleeding events and protect patient health.
Our nurses are acutely aware that safe administration, careful monitoring and proper storage are essential for maintaining effectiveness and regulatory compliance. Factor replacement therapy by infusion is the cornerstone of hemophilia management and significantly reduces bleeding episodes and increases quality of life. For partners, following these protocols ensures predictable quality metrics and builds trust with patients.
Newer Therapeutic Options
Medical advances in hemophilia A treatment, especially for patients with treatment inhibitors, are making care easier and more effective. Newer therapeutic options include subcutaneous therapies such as:
- Hemlibra (emicizumab): A once weekly (or less frequent) therapy that helps prevent bleeding events, reducing the need for frequent nurse visits.
- Hympavzi (marstacimab): A weekly therapy to prevent bleeding in patients with hemophilia A.
- Qfitlia (fitusiran): A once-monthly therapy that helps the blood clot more effectively, reducing the frequency of bleeding events.
- Alhemo (concizumab-mtci): A daily therapy that supports normal clotting to prevent bleeding.
Thoughtful patient selection helps ensure each individual receives the therapy best suited to their unique needs, balancing clinical effectiveness with organizational efficiency.
Emerging Therapies
Gene therapy and innovative non-factor treatments are the future of bleeding disorder management. They have the potential to reduce long-term treatment burden, supporting long-term reductions in total cost of care for payors and health systems.
For healthcare partners, staying prepared for emerging therapies helps future-proof care, deepen patient trust and promote leadership in leading-edge, patient-first treatments. When your organization understands and integrates these therapies, it can provide safer, more effective care to people with bleeding disorders, improve patient satisfaction and build operational resilience.
Specialized Nursing Competencies Required
Providing top-tier infusion services for patients with bleeding disorders demands specialized nursing expertise, clinical judgment and a commitment to patient safety. BrightStar Care delivers RN-led care that is dedicated to providing superior quality metrics for patients and reduced clinical risk for partner organizations.
Clinical Expertise and Training
Our infusion nurses bring advanced infusion therapy certifications and extensive hematology-specific nursing knowledge to every patient visit, offering several key advantages for our partner organizations. RN-led care ensures:
- Strict adherence to best practices and clinical standards
- Extensive experience with complex bleeding disorder treatment protocols to minimize complications
- Early recognition of adverse events to reduce clinical risk
Patient Assessment and Monitoring
Comprehensive and ongoing patient assessments are central to BrightStar Care’s treatment model. Our nurses continuously monitor treatment protocols, signs of inhibitor development and injection site reactions and adjust care plans to support optimal safety, comfort and outcomes. This results in several partner benefits:
- Reduced infusion-related complications
- Fewer hospital visits, readmissions and emergency interventions
- Improved medication adherence, confidence and overall patient experience
Emergency Preparedness
BrightStar Care registered nurses are trained in 24/7 clinical support protocols to provide rapid response to acute bleeding events, recognize anaphylaxis and severe reactions and provide seamless coordination with hematology care teams and emergency services to ensure:
- Immediate and appropriate emergency intervention
- Clear escalation protocols to specialists
- Continuous monitoring and communication to mitigate risk
Through specialized training, continuous monitoring and emergency preparedness, we deepen trust among patients and providers while empowering partners to deliver safe, high-quality infusion services and reduce clinical risk.
Safety, Compliance and Coordination
Our highly skilled infusion nurses follow partner-directed protocols to ensure alignment with value-based care goals and clinical objectives.
Safety Protocols and Quality Standards
We prioritize patient safety and regulatory compliance through key practices, such as:
- Medication verification and double-check procedures to prevent errors
- Proper storage temperature control to maintain therapy efficacy and safety
- Safe disposal of medical waste to protect patients, families and care staff
- Accurate documentation and adverse event reporting to support accountability and continuous quality improvement
Collaborative Care Coordination
We work closely with hemophilia treatment centers (HTCs), hematologists and specialty pharmacies to ensure clear communication and continuity of care for all patients. Additional support includes:
- Reducing administrative burden for hematology clinics, ensuring prior authorizations, documentation and coordination does not disrupt patient therapy schedules.
- Providing patient and family education to enhance treatment adherence and confidence.
- Serving as a seamless, trusted and reliable extension of the care team, promptly alerting providers to any clinical changes or concerns.
Strict adherence to safety protocols and proactive care coordination support clinical excellence and give partners confidence that their patients are in expert hands. Our systematic approach ensures that healthcare organizations, payors and third-party administrators (TPAs) can deliver exceptional quality metrics in a safe and compassionate environment.
Bleeding Disorder Infusion Expertise from BrightStar Care
BrightStar Care is a scalable workforce solution providing reliable RN-led home infusion support without overextending your internal teams.
Our Specialized Capabilities
Our care teams are trained to manage the full spectrum of home infusion therapies and care coordination, ensuring consistent protocols, training standards and patient experiences across all locations.
- RN-led teams with hematology experience: Our teams are specially trained to understand the nuances of bleeding disorder management.
- Factor replacement administration: Our protocols are designed to optimize patient safety, treatment adherence and comfort.
- Nationwide coverage for consistent care: We provide seamless care continuity for urban, suburban and rural patients in 41 states.
- Technology-enabled monitoring and reporting: Our teams provide real-time treatment insights (e.g., dose verification and adherence checks), allowing partners to monitor progress and outcomes as needed.
Patient Outcomes and Satisfaction
BrightStar Care’s dedication to safety, education and personalized attention is what drives measurable results for patients and partners.
- Reduced ER visits through proactive monitoring and timely interventions.
- Improved treatment adherence supported by education and regular follow-up.
- Enhanced patient independence and quality of life by empowering individuals to manage therapy confidently at home.
- Strong partnerships with HTCs and specialty pharmacies to ensure coordinated, seamless and integrated care.
With specialized nursing expertise, technology-enabled oversight and a focus on compassionate, patient-centered care, BrightStar Care ensures safe, effective bleeding disorder infusion therapy while supporting clinical excellence and collaborative partnerships.
Our RN-led teams help organizations, like yours, prevent complications that could lead to costly emergency interventions, improve patient outcomes and deepen trust with patients and their families.
Learn more about our partnership opportunities to find out how BrightStar Care can meet the specific needs of your infusion therapy patients.